Compare this test’s laboratory options
Activated Protein C-Resistance
Quest Diagnostics1 test optionFrom $388.58
Activated Protein C-Resistance
Quest DiagnosticsCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
DetailsActivated Protein C-Resistance – Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. Over 95% of the APC resistance phenotype is due to the Factor V Leiden mutation. The APC-Resistance assay is a plasma-based functional test for the determination of APC resistance caused by the factor V Leiden mutation.
What type of sample is required for this test?2 mL frozen platelet-poor citrated plasma collected in a 3.2% sodium citrate (light-blue-top) tube
Test ResourcesFor more information, please consult your healthcare provider.
Additional test information
Activated Protein C-Resistance – Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. Over 95% of the APC resistance phenotype is due to the Factor V Leiden mutation. The APC-Resistance assay is a plasma-based functional test for the determination of APC resistance caused by the factor V Leiden mutation.
Collection and processing
- Sample type: Plasma
- Fasting: No
- Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Plasma. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should be available in 2 – 5 business days after the sample is collected. Timing can change after collection or if a laboratory requires additional review.
About this test
DetailsActivated Protein C-Resistance - Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. Over 95% of the APC resistance phenotype is due to the Factor V Leiden mutation. The APC-Resistance assay is a plasma-based functional test for the determination of APC resistance caused by the factor V Leiden mutation.
What type of sample is required for this test?2 mL frozen platelet-poor citrated plasma collected in a 3.2% sodium citrate (light-blue-top) tube
Test ResourcesFor more information, please consult your healthcare provider.
Additional details
Activated Protein C-Resistance - Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. Over 95% of the APC resistance phenotype is due to the Factor V Leiden mutation. The APC-Resistance assay is a plasma-based functional test for the determination of APC resistance caused by the factor V Leiden mutation.
Highlighted health areas
- Cardiovascular
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- Activated Protein C Resistance