Revolutionizing Parkinsons Disease Treatment
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Causes of Parkinson’s Disease
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Di Monte, D.A., Chan, P. and Sandy, M.S. (1992), Glutathione in Parkinson’s disease: A link between oxidative stress and mitochondrial damage?. Ann Neurol., 32: S111-S115. https://doi.org/10.1002/ana.410320719. Several links exist between the two mechanisms of neuronal degeneration (i.e., oxygen radical production and mitochondrial damage) proposed to have a role in Parkinson’s disease. Indeed, mitochondria are critical targets for the toxic injury induced by oxygen radicals, and experimental evidence suggests that mitochondrial damage may cause an increased generation of oxygen radicals. A potentially important link between these two mechanisms of neurodegen-eration is glutathione.