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Direct Coombs
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Direct Coombs
Access Labcorp DrawCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
DetailsThe Direct Coombs test (also known as the direct antiglobulin test) detects antibodies or complement proteins bound to the surface of red blood cells. It is used to help diagnose conditions like autoimmune hemolytic anemia, hemolytic disease of the newborn, or transfusion reactions.
What type of sample is required for this test?Whole blood
Test ResourcesFor more information, please consult your healthcare provider.
Additional test information
The Direct Coombs test (also known as the direct antiglobulin test) detects antibodies or complement proteins bound to the surface of red blood cells. It is used to help diagnose conditions like autoimmune hemolytic anemia, hemolytic disease of the newborn, or transfusion reactions.
Collection and processing
- Sample type: Whole blood
- Fasting: No
- Estimated laboratory processing: Results should arrive 1 – 2 business days after the lab receives samples.
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Whole blood. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should arrive 1 – 2 business days after the lab receives samples.. Timing can change after collection or if a laboratory requires additional review.
About this test
DetailsThe Direct Coombs test (also known as the direct antiglobulin test) detects antibodies or complement proteins bound to the surface of red blood cells. It is used to help diagnose conditions like autoimmune hemolytic anemia, hemolytic disease of the newborn, or transfusion reactions.
What type of sample is required for this test?Whole blood
Test ResourcesFor more information, please consult your healthcare provider.
Additional details
The Direct Coombs test (also known as the direct antiglobulin test) detects antibodies or complement proteins bound to the surface of red blood cells. It is used to help diagnose conditions like autoimmune hemolytic anemia, hemolytic disease of the newborn, or transfusion reactions.
Highlighted health areas
- Hematology
- Immune System
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- Direct Antiglobulin Test (DAT)