Histamine Clearance Index

What this laboratory test evaluates

The Histamine Clearance Index™ is a targeted histamine intolerance test that evaluates the body’s ability to break down and eliminate histamine. This test helps practitioners assess impaired histamine clearance associated with reduced or inhibited diamine oxidase (DAO) activity, supporting clinical evaluation in patients with multi-system or allergy-like symptoms.

Additional test information

The Histamine Clearance Index™ helps evaluate impaired histamine elimination, which may occur as a result of reduced DAO activity. By assessing the functional capacity of DAO, the Histamine Clearance Index™ offers deeper clinical insight than standalone measurements of histamine or DAO levels.

Collection and processing

• Sample type: Whole blood
• Fasting: No
• Estimated laboratory processing: Results should arrive 7 business days after the lab receives samples.

How Sunridge uses laboratory information

Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.

Before requesting this test

Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.