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Lynch Syndrome Panel
Quest Diagnostics1 test optionFrom $7,271.33
Lynch Syndrome Panel
Quest DiagnosticsCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
DetailsLynch Syndrome Panel – Lynch syndrome is a leading cause of inherited colon cancer, affecting 2% to 4% of all cases of colorectal and endometrial cancer. This test looks for specific genetic changes (pathogenic variants) in the MLH1, MSH2, MSH6, PMS2, and EPCAM genes that can indicate Lynch syndrome.
Who should consider this test?This test is particularly important for individuals with a family history of colon cancer or those who have been diagnosed with colorectal or endometrial cancer at a young age.
What type of sample is required for this test?A 5 mL whole blood sample is needed, which can be collected in an EDTA (lavender-top) or ACD (yellow-top) tube.
Test Resources https://education.questdiagnostics.com/faq/FAQ243
Additional test information
This test is particularly important for individuals with a family history of colon cancer or those who have been diagnosed with colorectal or endometrial cancer at a young age.
Collection and processing
- Sample type: Whole blood
- Fasting: No
- Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Whole blood. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should be available in 2 – 5 business days after the sample is collected. Timing can change after collection or if a laboratory requires additional review.
About this test
DetailsLynch Syndrome Panel - Lynch syndrome is a leading cause of inherited colon cancer, affecting 2% to 4% of all cases of colorectal and endometrial cancer. This test looks for specific genetic changes (pathogenic variants) in the MLH1, MSH2, MSH6, PMS2, and EPCAM genes that can indicate Lynch syndrome.
Who should consider this test?This test is particularly important for individuals with a family history of colon cancer or those who have been diagnosed with colorectal or endometrial cancer at a young age.
What type of sample is required for this test?A 5 mL whole blood sample is needed, which can be collected in an EDTA (lavender-top) or ACD (yellow-top) tube.
Test Resources https://education.questdiagnostics.com/faq/FAQ243
Additional details
This test is particularly important for individuals with a family history of colon cancer or those who have been diagnosed with colorectal or endometrial cancer at a young age.
Highlighted health areas
- Genetics
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- Epcam
- Mlh1
- Msh2
- Msh6
- Pms2