Uterine Cancer · LIVING RESEARCH LIBRARY

Ongoing Research for Uterine Cancer Using Advanced Alternative Medicine

Explore positive published findings by substance, cancer biology, treatment interaction and quality-of-life outcome.

Every entry includes the original study title, year, concise finding and a direct PubMed link.

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Uterine Cancer

Living research library · positive published findings

Research organized by substance and finding

Browse 13 source-linked studies with the full title, publication year, research focus and a concise finding. Select any linked substance to move directly to its corresponding Sunridge page.

Berberine inhibits the development of endometrial cancer through circ_ZNF608/miR-377-3p/COX2 axis.

2022 · Metastasis and invasion

Berberine can inhibit the proliferation and metastasis of EC cells and promote apoptosis, which is related to the concentration.

Open study on PubMed →

Liposomal Curcumin Targeting Endometrial Cancer Through the NF-κB Pathway.

2018 · Apoptosis and cell death

In vitro, LC resulted in dose-dependent inhibition of proliferation, induction of apoptosis, and suppression of Ishikawa and HEC-1 cell motility.

Open study on PubMed →

Impact of the glutathione synthesis pathway on sulfasalazine-treated endometrial cancer.

2022 · Treatment response

Sulfasalazine treatment significantly decreased intracellular glutathione levels and induced apoptosis when combined with cisplatin in USC cell lines.

Open study on PubMed →

Melatonin suppresses tumor proliferation and metastasis by targeting GATA2 in endometrial cancer.

2024 · Metastasis and invasion

In addition, in vivo and in vitro experiments showed that MT inhibited the proliferation and metastasis of EC cells by upregulating GATA2 expression.

Open study on PubMed →

Associations of the gut microbiome with outcomes in cervical and endometrial cancer patients treated with pembrolizumab: Insights from the phase II PRIMMO trial.

2024 · Cancer biology and response

Here, exploratory studies of the gut microbiome (GM) are presented.

Open study on PubMed →

Interactions between microbiota and uterine corpus endometrial cancer: A bioinformatic investigation of potential immunotherapy.

2024 · Metastasis and invasion

In this regard, we used the same deconvolution of the TCGA database to analyze the microbiome that have a strong association with immune cells invasion with TME of UCEC patients.

Open study on PubMed →

Intratumor microbiome-derived butyrate enhances progesterone sensitivity by inducing ferroptosis in endometrial cancer.

2025 · Apoptosis and cell death

This study is the first to demonstrate the critical role of the EC tumor microbiome and its metabolite butyrate in modulating progesterone response in FPT.

Open study on PubMed →

Microbiome impacts quality of life in patients with endometrial cancer and benign gynecological conditions.

2025 · Quality of life and symptoms

We offer preliminary findings for foundational knowledge for future opportunities on improvement of QOL through microbiome modulation.

Open study on PubMed →

Integrating network pharmacology to investigate the mechanism of quercetin's action through AKT inhibition in co-expressed genes associated with polycystic ovary syndrome and endometrial cancer.

2025 · Cancer biology and response

Quercetin, a widely distributed natural flavonoid, has demonstrated potential therapeutic effects in managing both PCOS and EC.

Open study on PubMed →

Quercetin suppresses endometrial cancer stem cells via ERα-mediated inhibition of STAT3 signaling.

2025 · Cancer biology and response

This study aimed to evaluate the anti-tumor effects of Quercetin by targeting CSCs and suppressing their stemness properties.

Open study on PubMed →

Dual effects of metformin and resveratrol on compromising viability of endometrial cancer cells.

2026 · Tumor growth and proliferation

Metformin, commonly used for treating type 2 diabetes, and resveratrol, a natural polyphenol, can both decrease cancer cell proliferation by modulating the PI3K/Akt/mTOR pathway.

Open study on PubMed →

High-dose Ascorbate Exhibits Anti-proliferative and Anti-invasive Effects Dependent on PTEN/AKT/mTOR Pathway in Endometrial Cancer in vitro and in vivo.

2025 · Metastasis and invasion

In this study, high-dose ascorbate significantly inhibited cell proliferation and invasion, increased cellular stress and DNA damage, and induced cell cycle arrest and apoptosis in EC cells.

Open study on PubMed →

Retraction: Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP.

2025 · Cancer biology and response

The study reports retraction: Progesterone and calcitriol reduce invasive potential of endometrial cancer cells by targeting ARF6, NEDD9 and MT1-MMP.

Open study on PubMed →

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