CardioMetabolic Comprehensive

Catalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.

What this laboratory test evaluates

This test is one of Boston Heart's 3 curated cardiometabolic profiles. Since most adults have some degree of cardiometabolic risk, these profile have been designed to evaluate and monitor the extent of this risk in your patients.

Cardiovascular disease, type 2 diabetes, metabolic syndrome, and obesity are widespread and very common among patients. These lifestyle diseases are largely preventable, treatable, and reversible. The right combination of blood tests can unmask and monitor risk for serious health problems including premature death and dramatically reduced quality of life.

Advanced Lipid TestingRoutine lipid testing is insufficient to identify and monitor patients’ cardiometabolic risk adequately. Small Dense LDL-C, apoB, Lp(a), cholesterol production and absorption, fatty acids and HDL metabolism are all important for uncovering and treating hidden risk.

MetabolicsMonitoring glucose and HbA1c is critical for the prevention, early identification, treatment, and reversal of type 2 diabetes and cardiovascular risk.

InflammationAtherosclerosis is an inflammatory disease. After ruling out other causes of inflammation, C-reactive protein (CRP) is a strong independent predictor of CVD. Lowering CRP with statins in patients with normal LDL-C reduces CVD events. LpPLA2 measures inflammation specific to oxidized cholesterol plaque in the artery wall and reflects overall atherosclerotic burden. Oxidized phospholipid on apoB particles (OxPL-apoB) is highly pro-inflammatory and levels can be used to reclassify patients into higher or lower risk categories allowing for better personalized care. Inflammation can be reduced by losing weight if appropriate, normalizing lipids, glucose and blood pressure, eliminating tobacco and processed foods, making healthier dietary choices and increasing exercise and restful sleep.

ChemistriesElectrolytes, kidney function, liver function and other measures of normal metabolic activity are valuable tools for health assessment and patient management. Homocysteine, uric acid, vitamin D, and CoQ10 are each associated with CVD risk and can be improved with healthy lifestyle choices. When deficiencies are detected, it is important to understand the underlying cause to determine whether supplementation is appropriate to normalize levels.

Additional test information

Inclusive of the CardioMetabolic Expanded test, this panel evaluates the quality of the HDL using Boston Heart’s proprietary HDL Map. Markers of oxidative stress and inflammation along with Vitamin D and homocysteine allow the provider to evaluate additional causes for elevated lipids.

Collection and processing

• Sample type: Plasma, Serum, Whole blood
• Fasting: Yes
• Estimated laboratory processing: Results should arrive 14 business days after the lab receives samples.

How Sunridge uses laboratory information

Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.

Before requesting this test

Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.