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Centromere Abs
Quest Diagnostics1 test optionFrom $61.26
Centromere Abs
Quest DiagnosticsCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
Centromere B Antibody
This test is used to help diagnose a specific type of scleroderma known as CREST syndrome. CREST stands for Calcinosis, Raynaud's phenomenon, Esophageal immotility, Sclerodactyly, and Telangiectasia. Identifying the presence of Centromere B Antibody is key in diagnosing this condition.
What patients is this test right for?This test is particularly useful for individuals showing symptoms associated with CREST syndrome, such as:• Hard calcium deposits under the skin (Calcinosis)
• Sensitivity to cold in fingers and toes (Raynaud's phenomenon)
• Difficulty swallowing (Esophageal immotility)
• Tightening of the skin on the fingers (Sclerodactyly)
• Small, dilated blood vessels on the skin (Telangiectasia)
What type of sample is required for this test?1 mL serum. A blood sample is needed.
Test ResourcesResources are not provided for this test.
Additional test information
Centromere B Antibody – This test is used to help diagnose a specific type of scleroderma known as CREST syndrome. CREST stands for Calcinosis, Raynaud's phenomenon, Esophageal immotility, Sclerodactyly, and Telangiectasia. Identifying the presence of Centromere B Antibody is key in diagnosing this condition.
Collection and processing
- Sample type: Serum
- Fasting: No
- Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Serum. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should be available in 2 – 5 business days after the sample is collected. Timing can change after collection or if a laboratory requires additional review.
About this test
Centromere B Antibody
This test is used to help diagnose a specific type of scleroderma known as CREST syndrome. CREST stands for Calcinosis, Raynaud's phenomenon, Esophageal immotility, Sclerodactyly, and Telangiectasia. Identifying the presence of Centromere B Antibody is key in diagnosing this condition.
What patients is this test right for?This test is particularly useful for individuals showing symptoms associated with CREST syndrome, such as:• Hard calcium deposits under the skin (Calcinosis)
• Sensitivity to cold in fingers and toes (Raynaud's phenomenon)
• Difficulty swallowing (Esophageal immotility)
• Tightening of the skin on the fingers (Sclerodactyly)
• Small, dilated blood vessels on the skin (Telangiectasia)
What type of sample is required for this test?1 mL serum. A blood sample is needed.
Test ResourcesResources are not provided for this test.
Additional details
Centromere B Antibody - This test is used to help diagnose a specific type of scleroderma known as CREST syndrome. CREST stands for Calcinosis, Raynaud's phenomenon, Esophageal immotility, Sclerodactyly, and Telangiectasia. Identifying the presence of Centromere B Antibody is key in diagnosing this condition.
Highlighted health areas
- Autoimmune
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- Centromere b antibody