CICA Antibodies

What this laboratory test evaluates

This test evaluates tissue Transglutaminase (tTG)-specific IgG and IgA antibodies as well as total IgA. This measurement is useful to identify active disease. tTG is an enzyme produced by damaged enterocytes. The total antibody levels are also assessed to confirm the reliability of specific antibody levels to guide test interpretation. Active disease, as well as genetic risk suggests a need for dietary evaluation, which can be guided by an Alcat food sensitivity test. The CICA antibody test also measures IgG and IgA antibodies against saccharomyces cerevisiae ASCA (an indication of Crohn's disease) and antibodies against deamidated gliadan peptide, a risk factor for celiac disease.

Additional test information

The CICA Antibodies test evaluates serological markers for celiac disease and Crohn's disease. Increased levels of these antibodies indicate active disease.

Collection and processing

• Sample type: Serum
• Fasting: No
• Estimated laboratory processing: Results should arrive 10 business days after the lab receives samples.

How Sunridge uses laboratory information

Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.

Before requesting this test

Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.