Compare this test’s laboratory options
Comprehensive Hereditary Cancer Panel
Quest Diagnostics1 test optionFrom $8,024.10
Comprehensive Hereditary Cancer Panel
Quest DiagnosticsCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
DetailsThe Comprehensive Hereditary Cancer Panel tests for 66 genes linked to a wide range of hereditary cancers. This includes cancers that may affect the breast, colon, endometrium, stomach, urinary tract, ovary, pancreas, prostate, rectum, neuroendocrine system, thyroid, adrenal glands, paraganglia, and other tissues. If the test finds a pathogenic or likely pathogenic variant, it means there's an increased risk of developing certain cancers compared to the general population.
Who should consider this test?This test is particularly important for individuals with a family history of cancer, as it can help identify inherited cancer risks. Knowing your genetic risk can guide future monitoring and prevention strategies.
What type of sample is required for this test?5 mL of whole blood collected in an EDTA (lavender-top) or ACD (yellow-top) tube. A simple blood draw is needed.
Test Resources http://education.questdiagnostics.com/faq/FAQ217
Additional test information
This test is particularly important for individuals with a family history of cancer, as it can help identify inherited cancer risks.
Collection and processing
- Sample type: Whole blood
- Fasting: No
- Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Whole blood. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should be available in 2 – 5 business days after the sample is collected. Timing can change after collection or if a laboratory requires additional review.
About this test
DetailsThe Comprehensive Hereditary Cancer Panel tests for 66 genes linked to a wide range of hereditary cancers. This includes cancers that may affect the breast, colon, endometrium, stomach, urinary tract, ovary, pancreas, prostate, rectum, neuroendocrine system, thyroid, adrenal glands, paraganglia, and other tissues. If the test finds a pathogenic or likely pathogenic variant, it means there's an increased risk of developing certain cancers compared to the general population.
Who should consider this test?This test is particularly important for individuals with a family history of cancer, as it can help identify inherited cancer risks. Knowing your genetic risk can guide future monitoring and prevention strategies.
What type of sample is required for this test?5 mL of whole blood collected in an EDTA (lavender-top) or ACD (yellow-top) tube. A simple blood draw is needed.
Test Resources http://education.questdiagnostics.com/faq/FAQ217
Additional details
This test is particularly important for individuals with a family history of cancer, as it can help identify inherited cancer risks.
Highlighted health areas
- Women's health
- Genetics
- Men's health
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- Apc
- Atm
- Axin2
- Bard1
- Bmpr1a
- Brca1
- Brca2
- Brip1
- Cdh1
- Cdk4
- CDKN2A (p16, p14)
- Chek2
- Epcam
- Grem1
- Hoxb13
- Mlh1
- Msh2
- Msh3
- Msh6
- Mutyh
- Nf1
- Nthl1
- Palb2
- Pms2
- Pold1
- Pole
- Pten
- Rad51c
- Rad51d
- Smad4
View all 66 listed biomarkers
- Stk11
- Tp53
- Fh
- Max
- Men1
- Ret
- Sdha
- Sdhaf2
- Sdhb
- Sdhc
- Sdhd
- Tmem127
- Vhl
- Bap1
- Blm
- Cdkn1b
- Dicer1
- Fanca
- Fancc
- Fancm
- Flcn
- Galnt12
- Met
- Mitf
- Mre11 (mre11a)
- Nbn
- Pot1
- Ptch1
- Rad50
- Recql
- Smarca4
- Sufu
- Tsc1
- Tsc2
- Xrcc2
- EGFR