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DNA Ab., d-s
Quest Diagnostics1 test optionFrom $38.26
DNA Ab., d-s
Quest DiagnosticsCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
DNA (ds) Antibody
This test measures the presence of anti-double-stranded DNA (ds-DNA) antibodies in the blood. Positive dsDNA Antibody is detected in patients with active systemic lupus erythematosus (SLE) and approximately 20% of patients with Mixed Connective Tissue Disease and can help in diagnosing the autoimmune conditions and detect disease flares.
What patients is this test right for?This test is particularly relevant for individuals showing symptoms suggestive of autoimmune disorders like SLE or other autoimmune disorders, to confirm diagnosis, assess disease activity, and guide treatment decisions. Symptoms may include:• Skin rashes, especially with sun exposure
• A characteristic butterfly-shaped rash across the cheeks and nose
• Joint pain and swelling
• Fatigue
• Fever
• Hair loss
• Kidney problems
• Neurological symptoms
What type of sample is required for this test?1 mL serum.
Test ResourcesFor more information, please consult your healthcare provider.
Additional test information
DNA (ds) Antibody – This test measures the presence of anti-double-stranded DNA (ds-DNA) antibodies in the blood. Positive dsDNA Antibody is detected in patients with active systemic lupus erythematosus (SLE) and approximately 20% of patients with Mixed Connective Tissue Disease and can help in diagnosing the autoimmune conditions and detect disease flares.
Collection and processing
- Sample type: Serum
- Fasting: No
- Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Serum. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should be available in 2 – 5 business days after the sample is collected. Timing can change after collection or if a laboratory requires additional review.
About this test
DNA (ds) Antibody
This test measures the presence of anti-double-stranded DNA (ds-DNA) antibodies in the blood. Positive dsDNA Antibody is detected in patients with active systemic lupus erythematosus (SLE) and approximately 20% of patients with Mixed Connective Tissue Disease and can help in diagnosing the autoimmune conditions and detect disease flares.
What patients is this test right for?This test is particularly relevant for individuals showing symptoms suggestive of autoimmune disorders like SLE or other autoimmune disorders, to confirm diagnosis, assess disease activity, and guide treatment decisions. Symptoms may include:• Skin rashes, especially with sun exposure
• A characteristic butterfly-shaped rash across the cheeks and nose
• Joint pain and swelling
• Fatigue
• Fever
• Hair loss
• Kidney problems
• Neurological symptoms
What type of sample is required for this test?1 mL serum.
Test ResourcesFor more information, please consult your healthcare provider.
Additional details
DNA (ds) Antibody - This test measures the presence of anti-double-stranded DNA (ds-DNA) antibodies in the blood. Positive dsDNA Antibody is detected in patients with active systemic lupus erythematosus (SLE) and approximately 20% of patients with Mixed Connective Tissue Disease and can help in diagnosing the autoimmune conditions and detect disease flares.
Highlighted health areas
- Autoimmune
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- DNA (ds) Antibody