Laboratory test guide

DUTCH Cycle Mapping Plus (female only)

Available through Precision Analytical (DUTCH)

The DUTCH Cycle Mapping™ PLUS not only maps estrogen and progesterone through the monthly menstrual cycle, but also adds the comprehensiveness of all the hormone metabolites along with the cortisol awakening response (CAR). Hormonal…

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DUTCH Hormone Testing

Precision Analytical (DUTCH)
1 test optionFrom $1,249.50View tests ↓Close ↑

DUTCH Cycle Mapping Plus (female only)

Precision Analytical (DUTCH)

Details

Listed markers: 3-Hydroxyisovaleric Acid; 4-Hydroxyestrone; 2-Hydroxyestrone; Cortisone Night; Cortisone Evening; Cortisol Evening; Cortisol Night; Cortisol Morning - AM60; Cortisol Morning - AM30; Cortisol Waking; b-Pregnanediol; Cortisone Morning - AM60; Cortisone Morning - AM30; Cortisone Waking; Indican; b-Tetrahydrocortisol; Quinolinic Acid; Melatonin; Estriol; Metabolized Cortisol; Etiocholanolone; 8-Hydroxy-2-deoxyguanosine; 16-Hydroxyestrone; Vanillylmandelic Acid; Pyroglutamic Acid; Kynurenic Acid; Homovanillic Acid; 5a-Dihydrotestosterone; Xanthurenic Acid; b-Tetrahydrocortisone; a-Tetrahydrocortisol; Epi-Testosterone; 5b-Androstanediol; 5a-Androstanediol; Androsterone; a-Pregnanediol; Testosterone; Estradiol, Urine; Estrone, Urine; Progesterone, Urine; Dehydroepiandrosterone Sulfate; 2-methoxyestrone (2-m-e1); 2-hydroxyestradiol (2-oh-e2); 4-hydroxyestradiol (4-oh-e2); Creatinine (Urine); Methylmalonic Acid (MMA), Urine

Fasting: No

Results should arrive within 10 business days after the lab receives samples.

Minimum age: 9 Not available in: HI, PR, NJ, NY, RI

Related options may differ in markers and method; confirm with your clinician. Final prices and fees are confirmed before ordering.

SpecimenSaliva, Urine
Patient price$1,249.50
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What this laboratory test evaluates

The DUTCH Cycle Mapping™ PLUS not only maps estrogen and progesterone through the monthly menstrual cycle, but also adds the comprehensiveness of all the hormone metabolites along with the cortisol awakening response (CAR).

Hormonal balance is key. Fluctuating levels of estradiol and progesterone play a major role in a woman’s overall health. This panel is designed for cycling women who struggle with ongoing symptoms such as monthly migraines, fertility issues, or PCOS. The addition of the cortisol awakening response (CAR), a transient, immediate rise in cortisol upon awakening (distinct from the diurnal rhythm), provides a fuller assessment of hormone fluctuations, baseline stress response, and reflects a patient’s ability to cope with anticipated challenges. CAR also shows a patient’s perception of control around chronic stress, providing insight into HPA resiliency.

DUTCH CYCLE MAPPING™ PLUS Cycle Mapping™ PLUS combines the full picture of a woman’s cycle and adds salivary measurements of the Cortisol Awakening Response (CAR) to bring another important piece of the HPA axis into focus and answer important questions for patients with month-long symptoms, infertility, and PCOS.

WHEN IS CYCLE MAPPING™ PLUS RECOMMENDED?
• Women struggling with infertility
• Women with cycling hormones and no menses
• Partial hysterectomy (ovaries intact but no uterus)
• Ablations
• Women with irregular cycles
• PCOS
• If the luteal phase shifts from month-to-month
• Not sure when to test due to long or short cycles
• Women whose hormonal symptoms tend to fluctuate throughout the cycle
• PMS, mid-cycle spotting, migraines, etc.

WHEN IS CYCLE MAPPING™ PLUS NOT NEEDED? (DUTCH COMPLETE™ IS SUFFICIENT)
• Postmenopausal women
• Women on birth control
• Women with cycles that follow the expected pattern

Additional test information

Fluctuating levels of estradiol and progesterone can play a major role in a woman’s overall health, so understanding hormonal balance is key. The DUTCH Cycle Mapping™ PLUS is designed for cycling women who struggle with ongoing symptoms such as monthly migraines, fertility issues, or PCOS. The addition of the cortisol awakening response (CAR) provides practitioners with a fuller assessment of hormone fluctuations and baseline stress response and reflects a patient’s ability to cope with anticipated challenges. While for some women, testing reproductive hormones on a single day is sufficient – this test provides a more detailed clinical picture of the reproductive hormonal pattern that cannot be adequately captured without mapping the full cycle.

Collection and processing

  • Sample type: Saliva, Urine
  • Fasting: No
  • Estimated laboratory processing: Results should arrive within 10 business days after the lab receives samples.

How Sunridge uses laboratory information

Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.

Before requesting this test

Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.

About this test

The DUTCH Cycle Mapping™ PLUS not only maps estrogen and progesterone through the monthly menstrual cycle, but also adds the comprehensiveness of all the hormone metabolites along with the cortisol awakening response (CAR).

Hormonal balance is key. Fluctuating levels of estradiol and progesterone play a major role in a woman’s overall health. This panel is designed for cycling women who struggle with ongoing symptoms such as monthly migraines, fertility issues, or PCOS. The addition of the cortisol awakening response (CAR), a transient, immediate rise in cortisol upon awakening (distinct from the diurnal rhythm), provides a fuller assessment of hormone fluctuations, baseline stress response, and reflects a patient’s ability to cope with anticipated challenges. CAR also shows a patient’s perception of control around chronic stress, providing insight into HPA resiliency.

DUTCH CYCLE MAPPING™ PLUS Cycle Mapping™ PLUS combines the full picture of a woman’s cycle and adds salivary measurements of the Cortisol Awakening Response (CAR) to bring another important piece of the HPA axis into focus and answer important questions for patients with month-long symptoms, infertility, and PCOS.

WHEN IS CYCLE MAPPING™ PLUS RECOMMENDED?
• Women struggling with infertility
• Women with cycling hormones and no menses
• Partial hysterectomy (ovaries intact but no uterus)
• Ablations
• Women with irregular cycles
• PCOS
• If the luteal phase shifts from month-to-month
• Not sure when to test due to long or short cycles
• Women whose hormonal symptoms tend to fluctuate throughout the cycle
• PMS, mid-cycle spotting, migraines, etc.

WHEN IS CYCLE MAPPING™ PLUS NOT NEEDED? (DUTCH COMPLETE™ IS SUFFICIENT)
• Postmenopausal women
• Women on birth control
• Women with cycles that follow the expected pattern

Additional details

Fluctuating levels of estradiol and progesterone can play a major role in a woman’s overall health, so understanding hormonal balance is key. The DUTCH Cycle Mapping™ PLUS is designed for cycling women who struggle with ongoing symptoms such as monthly migraines, fertility issues, or PCOS. The addition of the cortisol awakening response (CAR) provides practitioners with a fuller assessment of hormone fluctuations and baseline stress response and reflects a patient’s ability to cope with anticipated challenges. While for some women, testing reproductive hormones on a single day is sufficient – this test provides a more detailed clinical picture of the reproductive hormonal pattern that cannot be adequately captured without mapping the full cycle.

Highlighted health areas

  • Women's health
  • Hormones

Biomarkers and report focus

The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.

  • 3-Hydroxyisovaleric Acid
  • 4-Hydroxyestrone
  • 2-Hydroxyestrone
  • Cortisone Night
  • Cortisone Evening
  • Cortisol Evening
  • Cortisol Night
  • Cortisol Morning - AM60
  • Cortisol Morning - AM30
  • Cortisol Waking
  • b-Pregnanediol
  • Cortisone Morning - AM60
  • Cortisone Morning - AM30
  • Cortisone Waking
  • Indican
  • b-Tetrahydrocortisol
  • Quinolinic Acid
  • Melatonin
  • Estriol
  • Metabolized Cortisol
  • Etiocholanolone
  • 8-Hydroxy-2-deoxyguanosine
  • 16-Hydroxyestrone
  • Vanillylmandelic Acid
  • Pyroglutamic Acid
  • Kynurenic Acid
  • Homovanillic Acid
  • 5a-Dihydrotestosterone
  • Xanthurenic Acid
  • b-Tetrahydrocortisone
View all 46 listed biomarkers
  • a-Tetrahydrocortisol
  • Epi-Testosterone
  • 5b-Androstanediol
  • 5a-Androstanediol
  • Androsterone
  • a-Pregnanediol
  • Testosterone
  • Estradiol, Urine
  • Estrone, Urine
  • Progesterone, Urine
  • Dehydroepiandrosterone Sulfate
  • 2-methoxyestrone (2-m-e1)
  • 2-hydroxyestradiol (2-oh-e2)
  • 4-hydroxyestradiol (4-oh-e2)
  • Creatinine (Urine)
  • Methylmalonic Acid (MMA), Urine

Important laboratory-testing information

This article is educational and does not diagnose a condition, establish medical care, or replace professional advice. Test availability, contents, pricing, eligibility, specimen instructions, and processing estimates can change. Sunridge must review the request and create an appropriate Fullscript order before payment. Follow the current instructions in your Fullscript account and laboratory kit, and discuss urgent or worsening symptoms with an appropriate medical professional.

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Scottsdale, Arizona 85260

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