Hepatitis C Viral RNA, Quantitative Real-Time PCR with Reflexes

What this laboratory test evaluates

DetailsHepatitis C Viral RNA, Quantitative Real-Time PCR with Reflexes – Hepatitis C (HCV) viral genotype is required prior to the initiation of antiviral therapy with direct acting agents. In addition, the FDA package insert recommends baseline NS5a resistance testing for HCV genotype 1a patients being evaluated for treatment with Zepatier, which contains the NS5a inhibitor elbasvir and the NS3 protease inhibitor grazoprevir.
This reflex code offers clinicians the option to obtain the HCV Viral load, HCV genotype and NS5a resistance testing with a single test order when considering treatment with Zepatier or in other circumstances where all three tests are warranted.

What type of sample is required for this test?3 mL plasma collected in an EDTA (lavender-top) tube

Test ResourcesFor more information, please consult your healthcare provider.

Additional test information

Hepatitis C Viral RNA, Quantitative Real-Time PCR with Reflexes – Hepatitis C (HCV) viral genotype is required prior to the initiation of antiviral therapy with direct acting agents. In addition, the FDA package insert recommends baseline NS5a resistance testing for HCV genotype 1a patients being evaluated for treatment with Zepatier, which contains the NS5a inhibitor elbasvir and the NS3 protease inhibitor grazoprevir.

Collection and processing

• Sample type: Plasma
• Fasting: No
• Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected

How Sunridge uses laboratory information

Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.

Before requesting this test

Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.