Compare this test’s laboratory options
Pregnenolone, LC/MS
Access Labcorp Draw · Access Medical Labs · Quest Diagnostics3 test optionsFrom $82.57
Pregnenolone, LC/MS
Access Labcorp Draw · Access Medical Labs · Quest DiagnosticsCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
DetailsPregnenolone, LC/MS – This test is key for distinguishing between different types of congenital adrenal hyperplasia (CAH), a group of genetic conditions affecting steroid hormone production. It's particularly useful for diagnosing rare CAH types and monitoring treatment effectiveness. Pregnenolone, a precursor to all steroid hormones, may show elevated levels in certain CAH types. This test is often conducted following a 17-hydroxyprogesterone test, especially when common CAH types are excluded but symptoms persist.
Who might need this test?Doctors might order this test for individuals showing symptoms of CAH, especially when initial screenings for common types come back negative. Symptoms can vary widely, depending on the specific enzyme deficiency and its impact on hormone balance.
What type of sample is required?0.5 mL serum collected in a red-top tube (no gel). It's crucial to freeze the sample immediately after collection to preserve its integrity until analysis.
Additional test information
This test is key for distinguishing between different types of congenital adrenal hyperplasia (CAH), a group of genetic conditions affecting steroid hormone production. It's particularly useful for diagnosing rare CAH types and monitoring treatment effectiveness.
Collection and processing
- Sample type: Serum
- Fasting: No
- Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Serum. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should be available in 2 – 5 business days after the sample is collected. Timing can change after collection or if a laboratory requires additional review.
About this test
DetailsPregnenolone, LC/MS - This test is key for distinguishing between different types of congenital adrenal hyperplasia (CAH), a group of genetic conditions affecting steroid hormone production. It's particularly useful for diagnosing rare CAH types and monitoring treatment effectiveness. Pregnenolone, a precursor to all steroid hormones, may show elevated levels in certain CAH types. This test is often conducted following a 17-hydroxyprogesterone test, especially when common CAH types are excluded but symptoms persist.
Who might need this test?Doctors might order this test for individuals showing symptoms of CAH, especially when initial screenings for common types come back negative. Symptoms can vary widely, depending on the specific enzyme deficiency and its impact on hormone balance.
What type of sample is required?0.5 mL serum collected in a red-top tube (no gel). It's crucial to freeze the sample immediately after collection to preserve its integrity until analysis.
Additional details
This test is key for distinguishing between different types of congenital adrenal hyperplasia (CAH), a group of genetic conditions affecting steroid hormone production. It's particularly useful for diagnosing rare CAH types and monitoring treatment effectiveness.
Highlighted health areas
- Women's health
- Hormones
- Adrenals and stress
- Men's health
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- Pregnenolone