PSA, Free and Total

What this laboratory test evaluates

DetailsPSA, Free and Total – This test is crucial for men over 50 with total PSA levels between 4.0 and 10.0 ng/mL, as it helps estimate the likelihood of prostate cancer. The % free PSA measurement can assist in deciding whether a biopsy is necessary, potentially avoiding unnecessary procedures.

Elevated PSA levels can indicate both benign and malignant conditions of the prostate. For men aged 50 or older, combining PSA tests with digital rectal exams enhances early detection of prostate cancer. After complete tumor resection, PSA levels should drop to undetectable levels, but may increase again if the disease recurs or if residual disease is present. Therefore, monitoring PSA levels is beneficial in managing prostate cancer patients.

Who should consider this test?Men over 50, especially those with PSA levels between 4.0 and 10.0 ng/mL, or those undergoing prostate cancer treatment and monitoring.

What type of sample is required for this test?2 mL frozen serum.

Test Resources https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq290

Additional test information

Elevated PSA levels can indicate both benign and malignant conditions of the prostate. For men aged 50 or older, combining PSA tests with digital rectal exams enhances early detection of prostate cancer. After complete tumor resection, PSA levels should drop to undetectable levels, but may increase again if the disease recurs or if residual disease is present. Therefore, monitoring PSA levels is beneficial in managing prostate cancer patients.

Collection and processing

• Sample type: Serum
• Fasting: No
• Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected

How Sunridge uses laboratory information

Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.

Before requesting this test

Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.