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SARS-CoV-2 Total Antibody, Spike, Semi-Quantitative
Quest Diagnostics1 test optionFrom $123.90
SARS-CoV-2 Total Antibody, Spike, Semi-Quantitative
Quest DiagnosticsCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
DetailsSARS-CoV-2 Total Antibody, Spike, Semi-Quantitative – This test is intended as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2 (COVID-19), indicating recent or prior infection.
The results of this semi-quantitative test should not be interpreted as an indication of degree of immunity or protection from reinfection.
Individuals who have been vaccinated with a SARS-CoV-2 spike or receptor-binding domain vaccine may be positive with this test; however, the clinical significance of a positive antibody result for individuals who have received a COVID-19 vaccine is unknown, in part because the test's performance characteristics have not been established for that population. It is not known how long antibodies persist following infection and if the presence of antibodies confers protective immunity.
This assay should not be used to diagnose acute SARS-CoV-2 infection.
What type of sample is required for this test?1 mL serum
Test ResourcesFor more information, please consult your healthcare provider.
Additional test information
SARS-CoV-2 Total Antibody, Spike, Semi-Quantitative – This test is intended as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2 (COVID-19), indicating recent or prior infection. The results of this semi-quantitative test should not be interpreted as an indication of degree of immunity or protection from reinfection.
Collection and processing
- Sample type: Serum
- Fasting: No
- Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Serum. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should be available in 2 – 5 business days after the sample is collected. Timing can change after collection or if a laboratory requires additional review.
About this test
DetailsSARS-CoV-2 Total Antibody, Spike, Semi-Quantitative - This test is intended as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2 (COVID-19), indicating recent or prior infection.
The results of this semi-quantitative test should not be interpreted as an indication of degree of immunity or protection from reinfection.
Individuals who have been vaccinated with a SARS-CoV-2 spike or receptor-binding domain vaccine may be positive with this test; however, the clinical significance of a positive antibody result for individuals who have received a COVID-19 vaccine is unknown, in part because the test's performance characteristics have not been established for that population. It is not known how long antibodies persist following infection and if the presence of antibodies confers protective immunity.
This assay should not be used to diagnose acute SARS-CoV-2 infection.
What type of sample is required for this test?1 mL serum
Test ResourcesFor more information, please consult your healthcare provider.
Additional details
SARS-CoV-2 Total Antibody, Spike, Semi-Quantitative - This test is intended as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2 (COVID-19), indicating recent or prior infection. The results of this semi-quantitative test should not be interpreted as an indication of degree of immunity or protection from reinfection.
Highlighted health areas
- Infectious Disease
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- SARS-CoV-2 Ab