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Scl-70 Abs
Quest Diagnostics1 test optionFrom $29.93
Scl-70 Abs
Quest DiagnosticsCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
DetailsScleroderma Antibody (Scl-70) – This test checks for the presence of Scl-70 antibodies, which are found in about 40% of individuals with progressive systemic sclerosis (PSS), a form of scleroderma. Scleroderma is a group of autoimmune diseases that cause the skin and connective tissues to harden and tighten.
What patients is this test right for?This test may be recommended for individuals showing symptoms of scleroderma, which can include:
• Hardening and tightening of the skin
• Swelling of the hands and feet
• Pain and stiffness in the joints
• Red spots on the skin
• Difficulty swallowing
• Facial changes, such as thinning of the lips
What type of sample is required for this test?1 mL serum. A blood sample is needed for this test.
Test ResourcesAdditional resources and information about this test are currently not available.
Additional test information
This test checks for the presence of Scl-70 antibodies, which are found in about 40% of individuals with progressive systemic sclerosis (PSS), a form of scleroderma. Scleroderma is a group of autoimmune diseases that cause the skin and connective tissues to harden and tighten.
Collection and processing
- Sample type: Serum
- Fasting: No
- Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Serum. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should be available in 2 – 5 business days after the sample is collected. Timing can change after collection or if a laboratory requires additional review.
About this test
DetailsScleroderma Antibody (Scl-70) - This test checks for the presence of Scl-70 antibodies, which are found in about 40% of individuals with progressive systemic sclerosis (PSS), a form of scleroderma. Scleroderma is a group of autoimmune diseases that cause the skin and connective tissues to harden and tighten.
What patients is this test right for?This test may be recommended for individuals showing symptoms of scleroderma, which can include:
• Hardening and tightening of the skin
• Swelling of the hands and feet
• Pain and stiffness in the joints
• Red spots on the skin
• Difficulty swallowing
• Facial changes, such as thinning of the lips
What type of sample is required for this test?1 mL serum. A blood sample is needed for this test.
Test ResourcesAdditional resources and information about this test are currently not available.
Additional details
This test checks for the presence of Scl-70 antibodies, which are found in about 40% of individuals with progressive systemic sclerosis (PSS), a form of scleroderma. Scleroderma is a group of autoimmune diseases that cause the skin and connective tissues to harden and tighten.
Highlighted health areas
- Autoimmune
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- Scleroderma (Scl-70) Antibody