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SHBG (Sex Hormone-Binding Globulin)
Quest Diagnostics · ZRT Laboratory2 test optionsFrom $29.40
SHBG (Sex Hormone-Binding Globulin)
Quest Diagnostics · ZRT LaboratoryCatalog information reviewed: August 24, 2026 by the Sunridge Medical clinical team.
What this laboratory test evaluates
DetailsSex Hormone Binding Globulin (SHBG) Test – This test measures the levels of SHBG in the blood, which binds to sex hormones such as testosterone, dihydrotestosterone, and estrogens. The amount of SHBG can change due to various conditions, affecting how much of these hormones are available in the body.
What patients is this test right for?This test might be recommended if you're experiencing symptoms or conditions that could affect or be affected by the levels of sex hormones in your body, such as:
• Pregnancy
• Hyperthyroidism or hypothyroidism
• Liver conditions like cirrhosis
• Use of oral estrogens or certain other medications
• Testosterone therapy
• Cushing's syndrome
• Acromegaly
• Obesity
What type of sample is required for this test?0.7 mL serum. A blood draw is needed.
Test Resources • https://education.questdiagnostics.com/faq/FAQ202
• https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq294
• https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq290
Additional test information
This test measures the levels of SHBG in your blood, which binds to sex hormones such as testosterone, dihydrotestosterone, and estrogens.
Collection and processing
- Sample type: Serum
- Fasting: No
- Estimated laboratory processing: Results should be available in 2 – 5 business days after the sample is collected
How Sunridge uses laboratory information
Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.
Before requesting this test
Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.
Common questions about this laboratory test
- What sample does this test require?
- The listed sample type is Bloodspot, Serum. Confirm current collection instructions in the approved order.
- Does this test require fasting?
- The current catalog record lists fasting as: No. Follow the instructions supplied with the approved order.
- How long does laboratory processing usually take?
- Results should be available in 2 – 5 business days after the sample is collected. Timing can change after collection or if a laboratory requires additional review.
About this test
DetailsSex Hormone Binding Globulin (SHBG) Test - This test measures the levels of SHBG in the blood, which binds to sex hormones such as testosterone, dihydrotestosterone, and estrogens. The amount of SHBG can change due to various conditions, affecting how much of these hormones are available in the body.
What patients is this test right for?This test might be recommended if you're experiencing symptoms or conditions that could affect or be affected by the levels of sex hormones in your body, such as:
• Pregnancy
• Hyperthyroidism or hypothyroidism
• Liver conditions like cirrhosis
• Use of oral estrogens or certain other medications
• Testosterone therapy
• Cushing's syndrome
• Acromegaly
• Obesity
What type of sample is required for this test?0.7 mL serum. A blood draw is needed.
Test Resources • https://education.questdiagnostics.com/faq/FAQ202
• https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq294
• https://www.questdiagnostics.com/healthcare-professionals/clinical-education-center/faq/faq290
Additional details
This test measures the levels of SHBG in your blood, which binds to sex hormones such as testosterone, dihydrotestosterone, and estrogens.
Highlighted health areas
- Women's health
- Hormones
- Men's health
Biomarkers and report focus
The exact analytes and report format can change. Confirm the current contents in the Fullscript order before payment.
- Sex Hormone Binding Globulin (SHBG)