Women’s Health & Breast Profile

What this laboratory test evaluates

The Women’s Health & Breast Profile Profile reports hormone levels and also calculates two important ratios. The Estrogen Quotient is a simple ratio of the cancer protective E3 relative to the proliferative estrogens E1 and E2, to assess breast cancer risk. The Pg/E2 ratio assesses the relationship between estradiol, which can drive cellular proliferation, and progesterone, which mitigates that growth and potentiates cellular differentiation.

Hormones are powerful molecules essential for maintaining physical and mental health. We frequently think of estrogen as being a female hormone, and testosterone as being a male hormone. But men AND women make both, plus several more that need to be in balance for optimum health. An imbalance of any one hormone can throw your physical and mental health out of balance, causing aggravating and even serious health problems.

One size does not fit all when it comes to hormones. For decades western medicine has prescribed hormone replacement therapy as if everyone needed the same thing and the same amount. Nothing could be further from the truth. Your hormones are like your fingerprints and in order to achieve optimal health, you need to know what your specific imbalances are. Female and male hormone tests can help identify these imbalances.

There are several ways to test for hormones (saliva, serum and urine). Saliva is the best method to test the active/bioavailable portion of hormones, which are reflective of tissue levels. If your patient is seeking bio-identical hormone replacement (BHRT), you'll need to know active hormone levels. In addition, if using a topical (transdermal) hormone preparation for treatment, saliva testing is the most accurate tool to measure and monitor hormone status.

Useful for: Research indicates this profile could be considered for those with:• Increased risk of developing breast cancer
• History of breast cancer or other hormonally sensitive cancers

Additional test information

A comprehensive preventative breast health program extends beyond imaging and lifestyle optimization, and includes accurate assessment and comprehensive treatment of demonstrated hormone imbalances. The Women’s Health and Breast Profile is an accurate, non-invasive tool to advance risk prevention and support you in providing exceptional care to your patients.
The Women’s Health and Breast Profile includes two risk assessment ratios, the Estrogen Quotient and the Pg/E2 ratio. Dr. Henry Lemon developed the Estrogen Quotient (EQ) which is a simple ratio of the cancer protective E3 to the proliferative estrogens E1 and E2. According to Dr. Lemon, the EQ provides an assessment of breast cancer risk, with a lower number (1.0) signifying a lower risk. Dr. Lemon’s work stated that for maximum protection, an optimal EQ is >1.5. The Pg/E2 ratio, developed by Dr. John Lee, illuminates the relationship between estradiol, which is a proliferative hormone, and progesterone, which balances estradiol and slows cellular proliferation. The information gained from this profile will help to further the conversation with your patients about targeted treatment options such as BHRT, nutraceutical and herbal supplementation, as well as potential lifestyle modifications.

Collection and processing

• Sample type: Saliva
• Fasting: No
• Estimated laboratory processing: Results should arrive 3 to 5 days after the lab receives samples.

How Sunridge uses laboratory information

Sunridge considers the medical question, symptoms, history, medications, prior results, and whether the finding could change care before recommending testing. A laboratory result is not interpreted in isolation and does not establish a diagnosis by itself.

Before requesting this test

Availability, collection requirements, eligibility, and processing estimates can change. Sunridge reviews each request and, when appropriate, creates the order through Fullscript. Follow the current instructions supplied with the approved order.